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Stereochemical survey of digitoxin monosaccharides: new anticancer analogues with enhanced apoptotic activity and growth inhibitory effect on human non-small cell …

HY Wang, W Xin, M Zhou, TA Stueckle… - ACS medicinal …, 2011 - ncbi.nlm.nih.gov
A stereochemically diverse array of monosaccharide analogues of the trisaccharide based cardiac
glycoside natural product digitoxin has been synthesized using a de novo asymmetric
approach. The analogues were tested for cytotoxicity against the NCI panel of 60 human ...

[CITATION] Stereochemical Survey of Digitoxin Monosaccharides ACS Med

HYL Wang, W Xin, M Zhou, TA Stueckle… - Chem. Lett, 2011
Cited by 2 - Related articles

Fluorescence spectrometric studies on the binding of puerarin to human serum albumin using warfarin, ibuprofen and digitoxin as site markers with the aid of …

G Zhang, N Zhao… - Journal of Luminescence, 2011 - Elsevier
The interaction of puerarin with human serum albumin (HSA) in pH 7.4 Tris–HCl buffer has been
investigated by fluorescence, Fourier transform infrared (FT-IR) and circular dichroism (CD)
spectroscopy. The results revealed the presence of static type of quenching mechanism ...

Biotransformation of extracted digitoxin from Digitalis lanata by Streptomyces

S Keshk, M Mostafa, F Tawk… - Die Pharmazie-An …, 2011 - ingentaconnect.com
Prof. Sherif Khesk, Chemistry Department, King Khalid University, PO Box 9004, Abha, The Kingdom
of Saudi Arabia sherifkeshk@yahoo.com ... The biotransformation of digitoxin and some of its
derivatives extracted from Digitalis lanata by Streptomyces isolated species was ...
Related articles - All 3 versions

[HTML] Ex Vivo Activity of Cardiac Glycosides in Acute Leukaemia

[HTML] from plos.orgH Hallböök, J Felth, A Eriksson, M Fryknäs… - PloS one, 2011 - dx.plos.org
... Digitoxin appeared most potent and IC 50 values for several patient samples were at
concentrations that may be achieved in the clinic. ... Digitoxin appeared most potent and IC 50 values
for several patient samples were at concentrations that may be achieved in the clinic. ...
Related articles - Cached - All 6 versions

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