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Management of Nausea and Vomiting in Cancer Patients

RM Navari, PP Province… - Cancer Management in Man: …, 2011 - Springer
... Activation of vagus and splanchnic nerves Medulla oblongata Chemoreceptor trigger zone
Vomiting center Increased afferent input to the chemoreceptor trigger zone and vomiting center
Fig. 25.1 Proposed pathways of chemotherapy-induced emesis Emetic center GABA ...
Related articles - All 2 versions

Anti-emetic drugs in oncology: pharmacology and individualization by pharmacogenetics

[HTML] from nih.govDA Perwitasari, H Gelderblom, J Atthobari… - International journal of …, 2011 - Springer
... Cytotoxic drugs can cause emesis through stimulation in the neuron-anatomical centers:
(1) the emetic center, (2) the area postrema or chemoreceptor trigger zone (CTZ),
and (3) the vagal nerve afferents [10]. The CTZ is sensitive ...
Cited by 1 - Related articles - All 5 versions

Intravenous, Oral, and the Combination of Intravenous and Oral Ramosetron for the Prevention of Nausea and Vomiting After Laparoscopic Cholecystectomy: A …

[HTML] from clinicaltherapeutics.comJH Ryu, YT Jeon, JW Hwang, A Oh, JY Moon… - Clinical …, 2011 - Elsevier
... First, they prevent serotonin from binding to 5-HT 3 receptors at the ends of the afferent
branches of the vagus nerve, which send signals directly to the vomiting center in the
medulla oblongata and to the chemoreceptor trigger zone in the brain. ...

Antiemetics for reducing vomiting related to acute gastroenteritis in children and adolescents

Z Fedorowicz, VA Jagannath… - status and date: New …, 2011 - Wiley Online Library
... Paralysis of the bowel develops with resultant abdominal distension, which induces further vom-
iting. Vomiting, from whatever cause, occurs because of the stimulation of the two centers located
in the brain, the chemoreceptor trigger zone and the vomiting center. ...

Oral ondansetron versus domperidone for symptomatic treatment of vomiting during acute gastroenteritis in children: multicentre randomized controlled trial

[PDF] from biomedcentral.comF Marchetti, A Maestro, F Rovere, D Zanon… - BMC …, 2011 - biomedcentral.com
... antagonists and act centrally by blocking the chemoreceptor trigger zone. They are used to
prevent or ... case reports. Domperidone is a D2 receptor antagonist that acts on the
chemoreceptor trigger zone. The medication also accelerates gastric emptying. ...
Cited by 1 - Related articles - All 6 versions

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