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The Physiology, Pharmacology and Future of P2X7 as an Analgesic Drug Target: Hype or Promise?

A Bhattacharya, RA Neff… - Current pharmaceutical …, 2011 - ncbi.nlm.nih.gov
P2X7 is an ATP-gated non-selective cation channel expressed primarily on cells of hematopoietic
origin, such as macrophages and microglia. Since the initial cloning of this channel, enormous
progress has been made in the understanding of the physiology, pharmacology and ...

Analgesic drug administration and attitudes about analgesia in cattle among bovine practitioners in the United States

VR Fajt, SA Wagner… - Journal of the American …, 2011 - Am Vet Med Assoc
The authors thank Caroline Hewson, Ian Dohoo, Kip Lempke, and Herman Barkema for providing
a copy of their survey of large animal veterinarians; M. Gatz Riddell Jr for providing access to
the AABP membership database; Justin Flynn for technical assistance with the survey; ...
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Analgesic Drug Discovery: Promising Future.

A Bhattacharya - Current pharmaceutical biotechnology, 2011 - ncbi.nlm.nih.gov
1. Curr Pharm Biotechnol. 2011 Apr 5. [Epub ahead of print] Analgesic Drug Discovery: Promising
Future. Bhattacharya A. Johnson & Johnson Pharmaceutical Research & Development LLC, 3210
Merryfield Row, San Diego, CA 92131, USA. abhatta2@its.jnj.com. ...

Method for treating pain

V Di Marzo, L De Petrocellis, S Malone… - US Patent …, 2011 - Google Patents
... After administration of an analgesic drug a stimulus of greater intensity or longer
duration is required before pain is experienced. In an indi- vidual suffering from
hyperalgesia an analgesic drug may have an anti-hyperalgesic effect. ...
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Analgesic efficacy and haemodynamic effects of nefopam in critically ill patients

G Chanques, M Sebbane… - British journal of …, 2011 - British Jrnl Anaesthesia
... chronic pain. 9–11 Although medical societies 1213 have recommended pain level
evaluation and analgesic drug titration for ICU patients, underutilization of analgesia
has been reported in the ICU setting in several countries. 414 ...
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