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… melphalan followed by ASCT has favorable safety and efficacy in selected patients with light chain deposition disease and light and heavy chain deposition disease

D Telio, J Shepherd, D Forrest, L Zypchen… - Bone Marrow …, 2011 - nature.com
Light chain and light and heavy chain deposition disease (LCDD and LHCDD) are plasma cell
dyscrasias in which aggregation and deposition of Ig components leads to organ
dysfunction. Although similar in principle to light chain (AL) amyloidosis, there are a ...
All 3 versions

[HTML] Indolent Mantle-Cell Lymphoma: Immunoglobulin Variable Region Heavy Chain Sequence Analysis Reveals Evidence of Disease 10 Years Prior to …

[HTML] from ascopubs.orgSAJ Rule, S Poplar, PAS Evans… - Journal of Clinical …, 2011 - jco.ascopubs.org
We report on a 60-year-old man who presented as an emergency with an acute abdomen in
2003. He had been completely well until shortly before this presentation with no symptoms of
note; specifically, he described no weight loss, no night sweats, no fevers, and no change ...
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Neurofilament heavy chain in CSF correlates with relapses and disability in multiple sclerosis

J Kuhle, D Leppert, A Petzold, A Regeniter… - Neurology, 2011 - AAN Enterprises
... Abstract. Objective: Neurodegeneration is now accepted as a pathologic hallmark of multiple
sclerosis (MS). We sought to discover whether CSF levels of neurofilament heavy chain protein
(NfH SMI35 ) correlate with disability, disease activity, or specific stages of MS. ...
Cited by 3 - Related articles - All 4 versions

Solitary Plasmacytoma of the Thracic Vertebra Presenting with Sudden Paraplegia and Back Pain: A Pathologic Case Report

T Terada - Pathology & Oncology Research, 2011 - Springer
... Plasma cell neoplasms may produce various immunoglobulins- related proteins, and produces
several associated disorders such as amyloidosis, M-proteinemia, urine Bence-Jones protein,
heavy chain disease, and light chain disease [1]. In the present case, the author ...
Related articles - All 3 versions

Exome Sequencing Identifies a DYNC1H1 Mutation in a Large Pedigree with Dominant Axonal Charcot-Marie-Tooth Disease

MN Weedon, R Hastings, R Caswell, W Xie… - The American Journal of …, 2011 - Elsevier
... we have identified a mutation in DYNC1H1 that causes Charcot-Marie-Tooth disease by using
exome sequencing in a large dominant pedigree. The mouse models also harboring mutations
in the homodimerization domain of cytoplasmic dynein heavy chain 1 support the ...

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