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[HTML] An Evolutionary Trade-Off between Protein Turnover Rate and Protein Aggregation Favors a Higher Aggregation Propensity in Fast Degrading Proteins

[HTML] from plos.orgG De Baets, J Reumers, JD Blanco… - PLoS Computational …, 2011 - dx.plos.org
In order to carry out their biological function, proteins need to fold into well-defined three-dimensional
structures. Protein aggregation is a process whereby proteins misfold into inactive and often
toxic higher order structures, which is implied in about 30 human diseases such as ...
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… Remodeling of the Rhodobacter sphaeroides Intracytoplasmic Membrane Results in a Slowing of the Electron Transfer Turnover Rate of Photochemical Reaction …

K Woronowicz, D Sha, RN Frese… - Biochemistry, 2011 - ACS Publications
Biochemistry is published by the American Chemical Society. 1155 Sixteenth Street NW,
Washington, DC 20036 Published by American Chemical Society. Copyright © American Chemical
Society. However, no copyright claim is made to original US Government works, or works ...
Cited by 1 - Related articles - All 2 versions

Influence of thyroidectomy on thyroxine metabolism and turnover rate in rats

H Nagao, T Imazu, H Hayashi… - Journal of …, 2011 - Soc Endocrinology
Little is known about the kinetics and metabolism of thyroid hormones in the hypothyroid
state. To investigate these factors, we developed a reliable method for measurement of serum
thyroxine (T 4 ), triiodothyronine (T 3 ), reverse-T 3 (rT 3 ) and stable isotope-labeled T 4 ([ ...
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Ribosome recycling depends on a mechanistic link between the FeS cluster domain and a conformational switch of the twin-ATPase ABCE1

[HTML] from pnas.orgD Barthelme, S Dinkelaker… - Proceedings of the …, 2011 - National Acad Sciences
... S1). The wild-type enzyme (ABCE1 WT ) has a Michaelis–Menten constant K M(MgATP)
of 0.7 mM and a turnover rate k cat of 12 ATP/ min (Fig. 1A and Table S1). ... The ATP turnover
rate k cat of various FeS cluster mutants (5 μM) is shown as insert. ...
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New nurses within the department reduce the turnover rate of project

Y Chen - 2011 - nursinglibrary.org
[22nd International Nursing Research Congress - Research Presentation] Purpose:áThe project
of new nurses within the department of the reasons for departure, and retention measures for
intervention, thereby reducing the turnover rate. Motivation from the manpower shortage ...
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