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Presenilins Promote the Cellular Uptake of Copper and Zinc and Maintain Copper Chaperone of SOD1-dependent Copper/Zinc Superoxide Dismutase Activity

…, I Volitakis, QX Li, K Laughton, G Evin… - Journal of Biological …, 2011 - ASBMB
Dyshomeostasis of extracellular zinc and copper has been implicated in β-amyloid
aggregation, the major pathology associated with Alzheimer disease. Presenilin mediates the
proteolytic cleavage of the β-amyloid precursor protein to release β-amyloid, and ...
Cited by 1 - Related articles - All 2 versions

Presenilins promote the cellular uptake of copper and zinc and maintain Cu-chaperone of sod1-dependent Cu/Zn superoxide dismutase activity

…, I Volitakis, QX Li, K Laughton, G Evin… - Journal of Biological …, 2011 - ASBMB
Dyshomeostasis of extracellular zinc and copper has been implicated in β-amyloid
aggregation, the major pathology associated with Alzheimer's disease. Presenilin mediates the
proteolytic cleavage of the β-amyloid precursor protein to release β-amyloid and ...
Cited by 2 - Related articles - All 2 versions

Decreased Expression of GGA3 Protein in Alzheimer's Disease Frontal Cortex and Increased Co-Distribution of BACE with the Amyloid Precursor Protein

…, AF Hill, CL Masters, C McLean, G Evin - Neurobiology of …, 2011 - Elsevier
BACE initiates the amyloidogenic processing of the amyloid precursor protein (APP) that results
in the production of Aβpeptides associated with Alzheimer's disease (AD). Previous studies
have indicated that BACE is elevated in the frontal cortex of AD patients. Golgilocalized γ- ...
Cited by 1 - Related articles - All 2 versions

p75NTR Regulates Aβ Deposition by Increasing Aβ Production But Inhibiting Aβ Aggregation with Its Extracellular Domain

[HTML] from jneurosci.org…, Y Sun, M Yang, Y Lim, G Evin… - The Journal of …, 2011 - Soc Neuroscience
Accumulation of toxic amyloid-β (Aβ) in the cerebral cortex and hippocampus is a major pathological
feature of Alzheimer's disease (AD). The neurotrophin receptor p75NTR has been proposed
to mediate Aβ-induced neurotoxicity; however, its role in the development of AD remains ...
Related articles - All 3 versions

Impact of mitral valve type on pulmonary hypertension and left atrial flow patterns: an in vitro preliminary study

M Evin, D Tanne, P Pibarot… - Computer Methods in …, 2011 - Taylor & Francis
The regression of pulmonary arterial pressure following valve replacement enables to decrease
the right ventricle after load but its normalisation is not always achieved. Patient prosthesis mismatch
has been shown to be a predictive factor for pulmonary arterial pressure (Tanné et al. ...

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