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[PDF] Coordinate loss of a microRNA and protein-coding gene cooperate in the pathogenesis of 5q-syndrome.

[PDF] from hematologylibrary.orgMS Kumar, A Narla, A Nonami… - …, 2011 - bloodjournal.hematologylibrary.org
... Page 4. 4 Introduction The 5q- syndrome is a subtype of myelodysplastic syndrome
(MDS) characterized by a macrocytic anemia, a normal or elevated platelet count,
and hypolobated micromegakaryocytes. 1 ... macrocytic anemia. 4 ...
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The role of haploinsufficiency of RPS14 and p53 activation in the molecular pathogenesis of the 5q-syndrome

[PDF] from pagepress.orgJ Boultwood - Pediatric Reports, 2011 - pagepress.org
... diseases including DBA and Treacher Collins syndrome.24,26 We have recently generated a
mouse model of the 5q- syndrome using large-scale chromo- somal engineering.27
Haploinsufficiency of the Cd74-Nid67 interval caused macrocytic anemia, prominent erythroid ...
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Anemia, Paresthesias, and Gait Ataxia in a 57-Year-Old Denture Wearer

[PDF] from hvsch.orgRB Sommerville… - Clinical Chemistry, 2011 - Am Assoc Clin Chem
... In addition, 5 months before the onset of his paresthesias, he was discovered to
have a macrocytic anemia that did not respond to treatment with vitamin B 12 and
folate. He ... What are some causes of macrocytic anemia? Could ...

Ineffective erythropoiesis with reduced red blood cell survival in serotonin-deficient mice

P Amireault, S Hatia, E Bayard… - Proceedings of the …, 2011 - National Acad Sciences
... The combination of these two defects causes TPH1 −/− animals to develop a phenotype of
macrocytic anemia. ... 1. TPH1 −/− mice display a phenotype of aregenerative macrocytic anemia.
(A–C) A significant decrease in the number of RBCs (7.5 ± 0.2 vs. ...

[HTML] Drawing to a Diamond flush

[HTML] from hematologylibrary.orgSR Ellis - Blood, 2011 - bloodjournal.hematologylibrary.org
... Diamond-Blackfan anemia is a rare congenital hypoplastic macrocytic anemia that typically
presents in the first year of life. The hypoplastic ... inactivation. 8 Yet, unlike DBA and 5q−,
individuals with TCS do not exhibit a macrocytic anemia. 9 ...
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