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Pharmacokinetics and pharmacodynamics of mycophenolic acid and its glucuronide early after renal transplantation

SE Tett, BA Atcheson, PJ Taylor… - 8th World …, 2011 - espace.library.uq.edu.au
The pharmacokinetics of mycophenolic acid and its glucuronide are complex. 42 renal transplant
recipients receiving mycophenolate mofetil and concomitant cyclosporin (n = 32) or tacrolimus
(n = 10) participated. Blood samples were taken on day 5 post-transplant. Free and total ...
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A Phase I Study of the Safety and Pharmacokinetics of the Hypoxia-Activated Prodrug TH-302 in Combination with Doxorubicin in Patients with Advanced Soft Tissue …

KN Ganjoo, LD Cranmer, JE Butrynski… - Oncology, 2011 - content.karger.com
Purpose: The purpose of this study was to determine the dose-limiting toxicities (DLT), maximum
tolerated dose (MTD), safety, pharmacokinetics and preliminary activity of TH-302, a
hypoxia-activated prodrug, in combination with doxorubicin in patients with advanced soft ...
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Association of Genetic Polymorphisms in the Influx Transporter SLCO1B3 and the Efflux Transporter ABCB1 With Imatinib Pharmacokinetics in Patients With Chronic …

Y Yamakawa, A Hamada, R Nakashima… - Therapeutic Drug …, 2011 - journals.lww.com
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information, please refer to our Privacy Policy. ... Skip Navigation Links Home > Current ...
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Pharmacokinetics and Pharmacodynamics of Therapeutic Doses of Basal Insulins NPH, Glargine, and Detemir After 1 Week of Daily Administration at Bedtime in Type …

P Lucidi, F Porcellati, P Rossetti… - Diabetes …, 2011 - Am Diabetes Assoc
RESULTS The glucose infusion rate area under the curve 0–32 h was greater for glargine than
for detemir and NPH (1,538 ± 688; 1,081 ± 785; and 1,170 ± 703 mg/kg, respectively; P <
0.05). Glargine suppressed endogenous glucose production more than detemir (P < 0.05) ...
Cited by 4 - Related articles - All 3 versions

Effect of 2 Weeks' Consumption of Pomegranate Juice on the Pharmacokinetics of a Single Dose of Midazolam: An Open-Label, Randomized, Single-Center, 2-Period …

S Misaka, R Nakamura, S Uchida, K Takeuchi… - Clinical …, 2011 - Elsevier
Sixteen subjects (11 men and 5 women) were enrolled and completed the study. The mean
(SD) age was 24.1 (4.8) years (range 22–40), mean body weight was 62.9 (8.8) kg (range
45.6–79.9). Differences in the mean AUC 0–∞ were 12.7 (4.4) and 14.2 (6.6) ng/mL/h in ...
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