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Optimal dosage regimen of meropenem for pediatric patients based on pharmacokinetic/pharmacodynamic consideration.

Y Ohata, Y Tomita, M Nakayama… - Drug metabolism and …, 2011 - ncbi.nlm.nih.gov
A population pharmacokinetic (PK) model for meropenem in Japanese pediatric patients with
various infectious diseases has been developed based on 116 plasma concentrations from 50
pediatric patients. The population PK parameters developed in this analysis are useful for ...
Cited by 1

2 Theoretical Models for Dermatokinetics of Therapeutic Agents

R Shi… - Dermatokinetics of Therapeutic Agents, 2011 - books.google.com
... Pharmacokinetics can be used in drug development to optimize therapy; it is used to determine
the dose, dosage regimen (the frequency of dosing), and dosage formula- tions. Choosing the
wrong dose, dosage regimen, or dosage form will render any drug ineffective. ...
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Evaluation of the Vancomycin Dosage Regimen Based on Serum Creatinine Used in Neonatal Intensive Care Unit

M Irikura, A Fujiyama, F Saita… - Pediatrics …, 2011 - Wiley Online Library
... Title: Evaluation of the Vancomycin Dosage Regimen Based on Serum Creatinine Used in
Neonatal Intensive Care Unit* Running title: Evaluation of the Vancomycin Dosage Regimen
Mitsuru Irikura,1 Ayako Fujiyama,1 Fumi Saita,1 Shiori Fukushima,1 Hiroki Kitaoka,2 Terumi ...

Pharmacokinetics and dosage regimen of cefpirome in febrile cross-bred calves

[PDF] from iums.ac.irN Rajput, VK Dumka… - Iranian Journal of Pharmacology …, 2011 - ijpt.iums.ac.ir
ABSTRACT The pharmacokinetics of cefpirome after a single intravenous injection of 10
mg.kg-1 was studied in febrile cross-bred calves. E. coli endotoxin was administered intravenously
to induce fever in calves. Blood samples were collected at different time intervals and ...
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Topiramate pharmacokinetics in infants and young children: Contribution of population analysis

M Bouillon-Pichault, R Nabbout, S Chhun, E Rey… - Epilepsy research, 2011 - Elsevier
... Available online 21 January 2011. Summary. Purpose. To determine the range of topiramate
(TPM) concentrations obtained in children under 4 with the recommended dosage regimen
(3–9 mg/kg/day) and to compare them to adult target ranges. Methods. ...
All 4 versions

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