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KA Salminen, A Meyer, L Jerabkova, LE Korhonen… - Phytomedicine, 2011 - Elsevier
The human cytochrome P450 (CYP) enzymes play a major role in the metabolism of endobiotics
and numerous xenobiotics including drugs. Therefore it is the standard procedure to test new
drug candidates for interactions with CYP enzymes during the preclinical development ...
All 3 versions
A Nakagawa, H Minami, JS Kim… - Nature …, 2011 - nature.com
The secondary metabolites of higher plants include diverse chemicals, such as alkaloids, isoprenoids
and phenolic compounds (phenylpropanoids and flavonoids). Although these compounds are
widely used in human health and nutrition, at present they are mainly obtained by ...
All 3 versions
AL Harvey, LC Young, AM Viljoen… - Journal of …, 2011 - Elsevier
The South African plant Sceletium tortuosum has been known for centuries for a variety of traditional
uses, and, more recently, as a possible source of anti-anxiety or anti-depressant effects. A standardised
extract Zembrin® was used to test for pharmacological activities that might be relevant to ...
P De Frenne, A Kolb, BJ Graae, G Decocq… - Plant …, 2011 - Wiley Online Library
... to increased chemical seed defence. The most widespread secondary compounds
involved in chemical plant defence containing N and occur- ring in the
Ranunculaceae are alkaloids (Larcher 2003). There- fore, we used a ...
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A Ivanova, J Serly, V Christov, B Stamboliyska… - Fitoterapia, 2011 - Elsevier
... Vinca alkaloids are substrates of ABC-type drug exporters but also inhibitors [9]. Based on these
observations we focused our recent research on the MDR inhibitory effects of various plant
alkaloids. ... Alkaloids comprise one of the largest groups of plant secondary metabolites. ...
Related articles - All 4 versions

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