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Dissection of the genetics of Parkinson's disease identifies an additional association 5′ of SNCA and multiple associated haplotypes at 17q21

[HTML] from nih.gov…, MA Brown, MA Brown, D Burn… - Human Molecular …, 2011 - Oxford Univ Press
We performed a genome-wide association study (GWAS) in 1705 Parkinson's disease (PD) UK
patients and 5175 UK controls, the largest sample size so far for a PD GWAS. Replication was
attempted in an additional cohort of 1039 French PD cases and 1984 controls for the 27 ...
Cited by 9 - Related articles - All 7 versions

A Wt1-Controlled Chromatin Switching Mechanism Underpins Tissue-Specific Wnt4 Activation and Repression

A Essafi, A Webb, RL Berry, J Slight, SF Burn… - Developmental Cell, 2011 - Elsevier
Wt1 regulates the epithelial-mesenchymal transition (EMT) in the epicardium and the reverse
process (MET) in kidney mesenchyme. The mechanisms underlying these reciprocal functions
are unknown. Here, we show in both embryos and cultured cells that Wt1 regulates Wnt4 ...

Morphology of All‐Solution‐Processed “Bilayer” Organic Solar Cells

…, IR Gentle, P Meredith, PL Burn - Advanced …, 2011 - Wiley Online Library
... Michael James , Karsten B. Krueger , Ian R. Gentle , Paul Meredith , * and Paul L. Burn *
Morphology of All-Solution-Processed “Bilayer” Organic ... [ 21 ] H. Cavaye , ARG Smith , M. James ,
A. Nelson , PL Burn , IR Gentle , S.-C. Lo , P. Meredith , Langmuir 2009, 25, 12800. ...
Cited by 11 - Related articles - All 3 versions

Calcium/NFAT signalling promotes early nephrogenesis

SF Burn, A Webb, RL Berry, JA Davies… - Developmental …, 2011 - Elsevier
A number of Wnt genes are expressed during, and are known to be essential for, early kidney
development. It is typically assumed that their products will act through the canonical β-catenin
signalling pathway. We have found evidence that suggests canonical Wnt signalling is ...
All 2 versions

Imputation of sequence variants for identification of genetic risks for Parkinson's disease: a meta-analysis of genome-wide association studies

…, JM Bras, K Brockmann, J Brooks, DJ Burn… - Lancet, 2011 - discovery.ucl.ac.uk
Nalls, MA and Plagnol, V and Hernandez, DG and Sharma, M and Sheerin, UM and Saad, M
and Simon-Sanchez, J and Schulte, C and Lesage, S and Sveinbjornsdottir, S and Arepalli, S
and Barker, R and Ben-Shlomo, Y and Berendse, HW and Berg, D and Bhatia, K and de ...
Cited by 14 - Related articles - Cached - All 5 versions

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