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Profibrotic Phenotype of Conjunctival Fibroblasts from Mucous Membrane Pemphigoid

VPJ Saw, E Schmidt, I Offiah, G Galatowicz… - The American journal of …, 2011 - Elsevier
Ocular mucous membrane pemphigoid is an immunobullous disease in which excessive conjunctival
fibrosis causes blindness, and the pathogenesis of scarring is incompletely understood. To establish
whether profibrotic fibroblasts with an altered phenotype exist in ocular mucous ...
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Differentiating antiepiligrin cicatricial pemphigoid from epidermolysis bullosa acquisita by indirect immunofluorescence of skin substrates lacking Type VII collagen or …

CP Chen, R Plunkett, R Grover… - Dermatologica Sinica, 2011 - Elsevier
Antiepiligrin cicatricial pemphigoid (AECP) is a chronic autoimmune subepidermal blistering
disease characterized by clinical features of cicatricial pemphigoid and circulating IgG antibasement
membrane autoantibodies directed against laminin 332. There is growing evidence of an ...
All 2 versions

Role of MHC Class II Genes in the pathogenesis of pemphigoid

LR Zakka, P Reche… - Autoimmunity Reviews, 2011 - Elsevier
Pemphigoid (Pg) is an autoimmune subepidermal blistering disease that affects the elderly
population. The phenotype can be Bullous Pemphigoid (BP), which primarily involves the
skin, or Mucous Membrane Pemphigoid (MMP), which primarily involves mucus ...

Generating Consensus Research Goals and Treatment Strategies for Pemphigus and Pemphigoid: The 2010 JC Bystryn Pemphigus and Pemphigoid Meeting

HY Schultz, LA Diaz, DA Sirois, VP Werth… - Journal of Investigative …, 2011 - nature.com
The third international meeting cosponsored by the International Pemphigus and Pemphigoid
Foundation (IPPF) and the National Institute of Arthritis and Musculoskeletal and Skin Diseases
was attended by approximately 130 scientists and clinicians representing the ...
All 3 versions

Type XVII collagen regulates lamellipod stability, cell motility and signaling to Rac1 by targeting bullous pemphigoid antigen 1e (BPAG1e) to {alpha} 6 {beta} 4 integrin …

KJ Hamill, SB Hopkinson, MF Jonkman… - The Journal of …, 2011 - ncbi.nlm.nih.gov
Rac1 activity, polarity, lamellipodial dynamics and directed motility are defective in keratinocytes
exhibiting deficiency in β4 integrin or knockdown of the plakin protein BPAG1e. The activity of
Rac, formation of stable lamellipodia and directed migration is restored in β4 integrin- ...
All 2 versions

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