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Pathogenic Relevance of IgG and IgM Antibodies against Desmoglein 3 in Blister Formation in Pemphigus Vulgaris

K Tsunoda, T Ota, M Saito, T Hata… - The American Journal of …, 2011 - Elsevier
Pemphigus vulgaris is an autoimmune disease caused by IgG antibodies against desmoglein
3 (Dsg3). Previously, we isolated a pathogenic mAb against Dsg3, AK23 IgG, which induces
a pemphigus vulgaris-like phenotype characterized by blister formation. In the present ...
All 2 versions

Desmoglein 3–specific CD4 T cells induce pemphigus vulgaris and interface dermatitis in mice

H Takahashi, M Kouno, K Nagao, N Wada… - J Clin …, 2011 - Am Soc Clin Investig
1 Department of Dermatology, Keio University School of Medicine, Shinjuku-ku, Tokyo,
Japan. 2 Center for Experimental Medicine and Systems Biology, Institute of Medical
Science, University of Tokyo, Minato-ku, Tokyo, Japan. 3 Department of Microbiology and ...

A genetic basis for the manipulation of sink–source relationships by the galling aphid Pemphigus batae

ZG Compson, KC Larson, MS Zinkgraf… - Oecologia, 2011 - Springer
Abstract We examined how the galling aphid Pemphigus batae manipulates resource translocation
patterns of resis- tant and susceptible narrowleaf cottonwood Populus angustifolia. Using
carbon-14 (14C)-labeling experiments in common garden trials, five patterns emerged. ...
Related articles - All 2 versions

IgG Autoantibodies Against Desmocollin 3 in Pemphigus Sera Induce Loss of Keratinocyte Adhesion

D Rafei, R Muller, N Ishii, M Llamazares… - The American Journal of …, 2011 - Elsevier
Pemphigus is considered an autoimmune bullous skin disorder associated with IgG against the
desmosomal components, desmoglein 3 (Dsg3) and desmoglein 1 (Dsg1). This concept is supported
by the in vitro and in vivo pathogenicity of anti-Dsg3/Dsg1 IgG and the mucosal blistering ...
Related articles - All 4 versions

Generating Consensus Research Goals and Treatment Strategies for Pemphigus and Pemphigoid: The 2010 JC Bystryn Pemphigus and Pemphigoid Meeting

HY Schultz, LA Diaz, DA Sirois, VP Werth… - Journal of Investigative …, 2011 - nature.com
The third international meeting cosponsored by the International Pemphigus and Pemphigoid
Foundation (IPPF) and the National Institute of Arthritis and Musculoskeletal and Skin Diseases
was attended by approximately 130 scientists and clinicians representing the ...
All 3 versions

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