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Aging impairs contraction-induced human skeletal muscle mTORC1 signaling and protein synthesis

[PDF] from skeletalmusclejournal.comCS Fry, MJ Drummond, EL Glynn… - Skeletal …, 2011 - skeletalmusclejournal.com
Background: Sarcopenia, the loss of skeletal muscle mass during aging, increases the risk for
falls and dependency. Resistance exercise (RE) training is an effective treatment to improve
muscle mass and strength in older adults, but aging is associated with a smaller amount ...
Cited by 2 - Related articles

T-tubule biogenesis and triad formation in skeletal muscle and implication in human diseases

L Al-Qusairi… - Skeletal Muscle, 2011 - skeletalmusclejournal.com
In skeletal muscle, the excitation-contraction (EC) coupling machinery mediates the translation
of the action potential transmitted by the nerve into intracellular calcium release and muscle
contraction. EC coupling requires a highly specialized membranous structure, the triad, ...
Cached

Novel mutations in NEB cause abnormal nebulin expression and markedly impaired muscle force generation in severe nemaline myopathy

MW Lawlor, CA Ottenheijm… - Skeletal …, 2011 - skeletalmusclejournal.com
We describe two siblings with severe NM, arthrogryposis and neonatal death due to two novel
NEB mutations; a point mutation in intron 13 and a frameshift mutation in exon 81. Levels of detectable
nebulin protein were significantly lower than those in normal control muscle biopsies or ...
Cached

Regulation of DMD pathology by an ankyrin-encoded miRNA

MS Alexander, JC Casar, N Motohashi… - Skeletal …, 2011 - skeletalmusclejournal.com
Duchenne muscular dystrophy (DMD) is an X-linked myopathy resulting from the production
of a nonfunctional dystrophin protein. MicroRNA (miRNA) are small 21- to 24-nucleotide RNA
that can regulate both individual genes and entire cell signaling pathways. Previously, we ...
Cached

Infusion with the antioxidant N‐acetylcysteine attenuates early adaptive responses to exercise in human skeletal muscle

AC Petersen, MJ McKenna, I Medved… - Acta …, 2011 - Wiley Online Library
This is an Accepted Article that has been peer-reviewed and approved for publication in the Acta
Physiologica, but has yet to undergo copy-editing and proof correction. Please cite this article
as an “Accepted Article”; doi: 10.1111/j.1748-1716.2011.02344.x

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