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SUMOylation promotes de novo targeting of HP1 [alpha] to pericentric heterochromatin

[PDF] from ejcho.infoC Maison, D Bailly, D Roche, RM de Oca… - Nature genetics, 2011 - nature.com
HP1 enrichment at pericentric heterochromatin is considered important for centromere
function. Although HP1 binding to H3K9me3 can explain its accumulation at pericentric
heterochromatin, how it is initially targeted there remains unclear. Here, in mouse cells, ...
Cited by 2 - Related articles - All 5 versions

FADS1 Genetic Variability Interacts with Dietary α-Linolenic Acid Intake to Affect Serum Non-HDL–Cholesterol Concentrations in European Adolescents

J Dumont, I Huybrechts, A Spinneker… - The Journal of …, 2011 - Am Soc Nutrition
Two rate-limiting enzymes in PUFA biosynthesis, Δ5- and Δ6-desaturases, are encoded by the
FADS1 and FADS2 genes, respectively. Genetic variants in the FADS1-FADS2 gene cluster
are associated with changes in plasma concentrations of PUFA, HDL- and ...
Related articles - All 3 versions

GAD2 on chromosome 10p12 is a candidate gene for human obesity

P Boutin, C Dina, F Vasseur, S Dubois, L Corset… - PLOS biology, 2011 - deakin.edu.au
The gene GAD2 encoding the glutamic acid decarboxylase enzyme (GAD65) is a positional
candidate gene for obesity on Chromosome 10p11–12, a susceptibility locus for morbid obesity
in four independent ethnic populations. GAD65 catalyzes the formation of γ-aminobutyric ...
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Identification of Novel Plant Peroxisomal Targeting Signals by a Combination of Machine Learning Methods and in Vivo Subcellular Targeting Analyses

T Lingner, AR Kataya, GE Antonicelli… - The Plant Cell …, 2011 - Am Soc Plant Biol
In the postgenomic era, accurate prediction tools are essential for identification of the proteomes
of cell organelles. Prediction methods have been developed for peroxisome-targeted proteins
in animals and fungi but are missing specifically for plants. For development of a predictor ...
Cited by 1 - Related articles - All 3 versions

Bone proteins PHEX and DMP1 regulate fibroblastic growth factor Fgf23 expression in osteocytes through a common pathway involving FGF receptor (FGFR) …

A Martin, S Liu, V David, H Li, A Karydis… - The FASEB Journal, 2011 - FASEB
ABSTRACT Fibroblastic growth factor 23 (FGF23) is a circulating phosphaturic hormone. Inactivating
mutations of the endopeptidase PHEX or the SIBLING protein DMP1 result in equivalent intrinsic
bone mineralization defects and increased Fgf23 expression in osteocytes. The ...
Cited by 1 - Related articles - All 2 versions

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