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Murine Syngeneic Graft-Versus-Host Disease Is Responsive to Broad-Spectrum Antibiotic Therapy

JA Brandon, CD Jennings… - The Journal of …, 2011 - Am Assoc Immnol
... In addition, periportal inflammation with bile duct infiltration (arrow) was seen in the livers isolated
from SGVHD animals (Fig. 5G). Interestingly, and in line with the colon length and plasma ALT
data, broad-spectrum antibiotic therapy completely eliminated colon inflammation ...
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Management of acute esophageal necrosis syndrome

CW McLaughlin, TD Person… - The Journal of Thoracic …, 2011 - AATS/WTSA
... The patient was resuscitated with intravenous fluids, a nasogastric tube was placed,
and she was started on an empiric course of broad-spectrum antibiotics before being
transferred to our institution for an impending surgical emergency. ...
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Identifying Patients Harboring Extended-Spectrum-{beta}-Lactamase-Producing Enterobacteriaceae on Hospital Admission: Derivation and Validation of a Scoring …

M Tumbarello, EM Trecarichi, M Bassetti… - Antimicrobial Agents …, 2011 - Am Soc Microbiol
... Similar figures emerged in the validation set. If patients with scores 3 initially receive
broad-spectrum antibiotic treatment that includes an agent active against ESBL-EKP (eg,
carbapenems), the probability of inappropriate therapy should be very low (<10%). ...
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Fecal Carriage and Shedding Density of CTX-M Extended-Spectrum {beta}-Lactamase-Producing Escherichia coli in Cattle, Chickens, and Pigs: Implications for …

RA Horton, LP Randall, EL Snary… - Applied and …, 2011 - Am Soc Microbiol
... However, one of the acknowledged risk factors for the selection of ESBL-producing bacteria is
the use of antibiotics (10, 30). "Third-generation" (ie, expanded-spectrum antibiotics) and
"fourth-generation" (broad-spectrum antibiotics with enhanced activity against Gram-positive ...
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In Vivo Efficacy of the Novel Aminoglycoside ACHN-490 in Murine Infection Models

N Reyes, JB Aggen… - Antimicrobial Agents and …, 2011 - Am Soc Microbiol
... Aminoglycosides are broad-spectrum antibiotics with particular clinical utility against
life-threatening infections. ... 1963. Pharmacology of gentamicin, a new broad-spectrum antibiotic,
p. 138-147. Antimicrob. Agents Chemother. 1962. 4. Bratu, S., et al. 2005. ...
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