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Fibroblast Growth Factor-2 Promotes in Vitro Mitral Valve Interstitial Cell Repair through Transforming Growth Factor-[beta]/Smad Signaling

L Han… - The American Journal of Pathology, 2011 - Elsevier
Transforming growth factor (TGF)-β and fibroblast growth factor (FGF)-2 both promote repair
in valve interstitial cell (VIC) injury models; however, the relationship between TGF-β and
FGF-2 in wound repair are not well understood. VIC confluent monolayers were wounded ...
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The Effects of Combined Cyclic Stretch and Pressure on the Aortic Valve Interstitial Cell Phenotype

P Thayer, K Balachandran, S Rathan… - Annals of biomedical …, 2011 - Springer
1W.H. Coulter School of Biomedical Engineering, Georgia Institute of Technology, Atlanta,
GA, USA; 2School of Chemical and Biomolecular Engineering, Georgia Institute of
Technology, Atlanta, GA, USA; and 3Department of Cardiology, Emory University, Atlanta, ...
Cited by 4 - Related articles - All 4 versions

Role of the Rho pathway in regulating valvular interstitial cell phenotype and nodule formation

X Gu… - American Journal of Physiology-Heart …, 2011 - Am Physiological Soc
The differentiation of valvular interstitial cells (VICs) to a myofibroblastic or osteoblast-like phenotype
is commonly found in calcific valvular stenosis, although the molecular-level mechanisms of
this process remain poorly understood. Due to the role of the Rho pathway in various ...
Cited by 1 - Related articles - All 3 versions

Regulation of valvular interstitial cell phenotype and function by hyaluronic acid in 2-D and 3-D culture environments

KJ Rodriguez, LM Piechura… - Matrix Biology, 2011 - Elsevier
Disruption of the extracellular matrix (ECM) is frequently found in calcific aortic valve disease
(CAVD), yet the role of ECM components in valvular interstitial cell (VIC) function and dysfunction
remains poorly understood. This study examines the contributions of exogenous and ...
Cited by 2 - Related articles - All 2 versions

[CITATION] Persistent [beta]-Catenin Activation Underlies Senescence of Interstitial Cell of Cajal (ICC) Stem Cells in Naturally Aging Mice

DT Asuzu, Y Hayashi, MR Bardsley, G Farrugia… - Gastroenterology, 2011 - Elsevier

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