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Coronin 2A mediates actin-dependent de-repression of inflammatory response genes

W Huang, S Ghisletti, K Saijo, M Gandhi, M Aouadi… - Nature, 2011 - nature.com
Toll-like receptors (TLRs) function as initiators of inflammation through their ability to sense
pathogen-associated molecular patterns and products of tissue damage 1, 2 . Transcriptional
activation of many TLR-responsive genes requires an initial de-repression step in which ...
Cited by 4 - Related articles - All 5 versions

The G‐protein coupled bile acid receptor Gpbar1 (TGR5) negatively regulates hepatic inflammatory response through antagonizing Nuclear Factor κB

YD Wang, WD Chen, D Yu, BM Forman… - Hepatology, 2011 - Wiley Online Library
... mice show more severe liver necroses and inflammation compared with wild-type (WT) mice.
Activation of TGR5 by its agonist ligand inhibits the expression of inflammatory mediators in
response to NF-κB activation induced by LPS in WT but not TGR5 -/- mouse liver. ...
Related articles - All 2 versions

Sphingosine-1-phosphate lyase deficiency produces a pro-inflammatory response while impairing neutrophil trafficking

ML Allende, M Bektas, BG Lee, E Bonifacino… - Journal of Biological …, 2011 - ASBMB
Sphingosine-1-phosphate (S1P) lyase catalyzes the degradation of S1P, a potent signaling
lysosphingolipid. Mice with an inactive S1P lyase gene are impaired in the capacity to degrade
S1P, resulting in highly elevated S1P levels. These S1P lyase-deficient mice have low ...
Cited by 2 - Related articles - All 4 versions

A Multiscale Model Of The Inflammatory Response At The Pulmonary Airway And Vascular Interface

SD Amin… - American Journal of Respiratory and Critical …, 2011 - Am Thoracic Soc
Acute inflammation of the airways and surrounding tissue, either induced by inhaled environmental
agents or immunological stimuli, is coordinated by many interacting mechanisms. Chemical agents
diffuse throughout and bind to tissues, eliciting responses such as stress generation in ...
All 3 versions

The relation between acute changes in the systemic inflammatory response and plasma 25-hydroxyvitamin D concentrations after elective knee arthroplasty

D Reid, BJ Toole, S Knox, D Talwar… - … American Journal of …, 2011 - Am Soc Nutrition
1 From the Department of Anaesthesia, Faculty of Medicine (DR, JH, and JK), the Department
of Clinical Biochemistry (BJT, SK, DT, DSJO, SB, and AMW), and the Department of Surgery,
Faculty of Medicine (DCM), University of Glasgow, Royal Infirmary, Glasgow, United ...
Cited by 7 - Related articles - All 4 versions

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