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MONOCLONAL ANTIBODY 175 TAGETING THE EGF RECEPTOR AND DERIVATIVES AND USES THEREOF

…, E Stockert, S Stockert, LJ Old - US Patent …, 2011 - freepatentsonline.com
The present invention relates to antibodies, particularly antibody 175, and fragments thereof
or antibodies derived therefrom, which bind to the EGF receptor, particularly to amplified or overexpressed
epidermal growth factor receptor (EGFR) and to the de2-7 EGFR truncation of the EGFR. ...
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Antibody-targeted NY-ESO-1 to mannose receptor or DEC-205 in vitro elicits dual human CD8+ and CD4+ T cell responses with broad antigen specificity

…, LZ He, T Keler, K Odunsi, LJ Old… - The Journal of …, 2011 - Am Assoc Immnol
Immunization of cancer patients with vaccines containing full-length tumor Ags aims to elicit specific
Abs and both CD4 + and CD8 + T cells. Vaccination with protein Ags, however, often elicits only
CD4 + T cell responses without inducing Ag-specific CD8 + T cells, as exogenous protein ...
Cited by 6 - Related articles - All 5 versions

… OF PERITONEAL DIALYSIS IN ELDERLY PATIENTS BY CLASSIFYING THE AGE INTO YOUNG-OLD, OLD AND OLDEST-OLD: TWO-CENTER STUDY IN …

YS Kang, JJ Cha, YY Hyun, MH Lee… - NDT …, 2011 - ndtplus.oxfordjournals.org
INTRODUCTION AND AIMS: During continuous ambulatory peritoneal dialysis (CAPD), various
morphological and functional changes occur in the peritoneum, leading to peritoneal
fibrosis, thickening, and ultrafiltration failure. The previous studies reported the protective ...

GH, GH receptor antagonists, GH receptor'knock-outs': a story of fat old mice

J Kopchick - 2011 - endocrine-abstracts.org
In this talk I will describe several genes that have been implicated in the action of GH as it relates
to aging. Much of the data is derived from two dwarf and one giant strain of mice produced in
our laboratory that possess very different life spans. One of the dwarf lines contains a ...
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Oxidative stress alters renal D1 and AT1 receptor functions and increases blood pressure in old rats

G Chugh, MF Lokhandwala… - American Journal of …, 2011 - Am Physiological Soc
Aging is associated with an increase in oxidative stress and blood pressure (BP). Renal dopamine
D1 (D1R) and angiotensin II AT1 (AT1R) receptors maintain sodium homeostasis and BP. We
hypothesized that age-associated increase in oxidative stress causes altered D1R and ...
Cited by 1 - Related articles - All 4 versions

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