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Central dogma at the single-molecule level in living cells

GW Li… - Nature, 2011 - nature.com
Gene expression originates from individual DNA molecules within living cells. Like many
single-molecule processes, gene expression and regulation are stochastic, that is, sporadic in
time. This leads to heterogeneity in the messenger-RNA and protein copy numbers in a ...

Revisiting the central dogma one molecule at a time

[PDF] from berkeley.eduC Bustamante, W Cheng… - Cell, 2011 - Elsevier
The faithful relay and timely expression of genetic information depend on specialized molecular
machines, many of which function as nucleic acid translocases. The emergence over the last
decade of single-molecule fluorescence detection and manipulation techniques with nm ...
Cited by 6 - Related articles - All 4 versions

Protein-protein interactions and cancer: Targeting the central dogma

L Garner, D Janda - Current topics in medicinal chemistry, 2011 - ingentaconnect.com
Amanda L. Garner 1,2 and Kim D. Janda 1,2,3, * ... 1Departments of Chemistry and Immunology
and Microbial Science, 2The Skaggs Institute for Chemical Biology, and 3The Worm Institute
for Research and Medicine, The Scripps Research Institute, 10550 North Torrey Pines ...
Cited by 1 - Related articles - All 4 versions

The central dogma: From Danielle steel to Steely Dan.

MW Love - Biochemistry and molecular biology education: a …, 2011 - ncbi.nlm.nih.gov
1. Biochem Mol Biol Educ. 2011 Mar;39(2):180. doi: 10.1002/bmb.20485.
The central dogma: From Danielle steel to Steely Dan. Love MW.
marthalove9@yahoo.com. PMID: 21445914 [PubMed - in process].

Unstable genes unstable mind: Beyond the central dogma of molecular biology

MV Hegde… - Medical Hypotheses, 2011 - Elsevier
Schizophrenia has a polygenic mode of inheritance and an estimated heritability of over
80%, but success in understanding its genetic underpinnings to date has been modest. Unlike
in trinucleotide neurodegenerative disorders, the phenomenon of genetic anticipation ...
Related articles - All 4 versions

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